Focused ultrasound, or FUS therapy, is a non-invasive therapeutic technology that uses ultrasonic energy to target tissue deep within the body without the need for incisions or radiation. Currently, this technology is being researched as a way to target specific areas of the brain involved in neurological disorders.
Neuromodulation
Temporal Lobe Epilepsy (TLE), is the most common type of focal epilepsy, where the epileptogenic zone is located in one specific part of the brain. In TLE, this epileptogenic region often is the hippocampus, which is an important structure in memory formation and spatial navigation. In this structure the excitatory neurons are overactivated, resulting in seizures. Using FUS we can specifically target this location in order to modulate these neurons and suppress the seizures.
Our current research focusses on:
1. Finding the optimal parameters for seizure suppression in a epileptic mouse model.
2. Researching focused ultrasound therapy in patients.
Researcher(s) involved in this research line:
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Robrecht Raedt
Professor Robrecht Raedt, PhD, is leading the preclinical 4Brain research lab, with a main focus on new treatment techniques as a treatment for various neuropsychiatric disorders (epilepsy, stroke, multiple sclerosis, glioblastoma).
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