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Brain Health
Read more about our Brain Health research here.
Boon P. et al (2025) - A roadmap toward promoting and improving brain health in Europe and closing the awareness and funding gap
Boon P. et al. (2024) - A strategic neurological research agenda for Europe : towards clinically relevant and patient-centred neurological research priorities
Vonck K. et al. (2020) - Neurological manifestations and neuro-invasive mechanisms of the severe acute respiratory syndrome coronavirus type 2
Lagast S. et al. (2020) - Heart rate, electrodermal responses and frontal alpha asymmetry to accepted and non-accepted solutions and drinks
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Cerebrovascular diseases
Read more about our Cerebrovascular research here.
Proesmans S. et al. (2025) - Perihematomal changes in glucose metabolism and cell counts in the rat collagenase model for intracerebral hemorrhage
Lajtos M. et al. (2025) - Studying metabolic brain connectivity using 2-deoxy-2-[18F]fluoro-D-glucose dynamic positron emission tomography at the single-subject level
Germonpré C. et al. (2021) - Seizures and interictal epileptiform activity in the rat collagenase model for intracerebral hemorrhage
Proesmans S. et al. (2021) - Voxel-based analysis of [18F]-FDG brain PET in rats using data-driven normalization
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Epilepsy
Read more about our Epilepsy research here.
2026
Cocquyt E. et al. (2026) - Effects of deep brain stimulation on spontaneous language production in people with Parkinson’s disease: a preliminary study
Mary A. et al. (2026) - Transcutaneous vagus nerve stimulation enhances episodic memory across valences and memory stages
Parys A. et al. (2026) - Photo‐reversible coumarin‐based networks with tailorable properties for extrusion 3D printing and adhesive applications
Parys A. et al. (2026) - Radiopaque coating for improved implantability and in vivo imaging of neural probes
2025
Craey E. et al. (2025) - Feedback control of excitability and high K+ induced epileptiform bursts in male rat hippocampal slices with a photocaged adenosine A1 receptor agonist
Weyn L. et al. (2025) - Computational analysis of optogenetic inhibition of CA1 neurons using a data-efficient and interpretable potassium and chloride conducting opsin model
Schumacher S. et al. (2025) - Astrocyte-Targeted connexin43 Hemichannel Inhibition Prevents Radiation-Induced Energy Transporter Decrease in Neurons and Astrocytic proBDNF Transport to Synapses
Spanoghe J. et al. (2025) - Photopharmacological activation of adenosine A1 receptor signaling suppresses seizures in a mouse model for temporal lobe epilepsy
Spanoghe J. et al. (2025) - Effects of intracerebroventricular administration of dimethyl sulfoxide on hippocampal electrophysiology in mice
Caestecker S. et al. (2025) - Chemogenetic modulation of the rat locus coeruleus alters hippocampal noradrenaline release and modulates perforant path-evoked responses
Algoet C. et al. (2025) - Repetitive transcranial magnetic stimulation for refractory and super-refractory status epilepticus : a systematic review
Hogeveen L. et al. (2025) - The effectiveness of cenobamate in patients treated with vagus nerve stimulation for drug resistant epilepsy
Caestecker S. et al (2025) - The locus coeruleus-noradrenergic system in the healthy and diseased brain : a narrative review
Hogeveen L. et al. (2025) - Therapeutic use of transcranial ultrasound for epilepsy : a review
2024
Lescrauwaet E. et al. (2024) - Investigating the working mechanism of transcranial direct current stimulation
Carrette S. et al. (2024) - Exploration of theta burst-induced modulation of transcranial magnetic stimulation-evoked potentials over the motor cortex
Vergaelen M. et al. (2024) - Increased dentate gyrus excitability in the intrahippocampal kainic acid mouse model for temporal lobe epilepsy
Bachmann H. et al. (2024) - Vagus nerve stimulation enhances remyelination and decreases innate neuroinflammation in lysolecithin-induced demyelination
Teuwen D. et al. (2024) - Challenges to epilepsy management in Rwandan women living with epilepsy
Garrez I. et al. (2024) - Converging evidence on the high prevalence of epilepsy in Rwanda : response to the commentary 'High prevalence of epilepsy in Southern and Northern Rwanda : myth or reality?'
2023
Larsen L. et al. (2023) - Hippocampal seizures differentially modulate locus coeruleus activity and result in consistent time-locked release of noradrenaline in rat hippocampus
Acharya A. et al. (2023) - In vivo inhibition of epileptiform afterdischarges in rat hippocampus by light-activated chloride channel, stGtACR2
Schoeter R. et al. (2023) - Quantitative analysis of the optogenetic excitability of CA1 neurons
Charalambous M. et al (2023) - Translational veterinary epilepsy : a win-win situation for human and veterinary neurology
Vonck K. et al. (2023) - Usage and impact of patient-reported outcomes in epilepsy
2022
Desloovere J. et al. (2022) - Chemogenetic seizure control with clozapine and the novel ligand JHU37160 outperforms the effects of Levetiracetam in the intrahippocampal kainic acid mouse model
Carrette S. et al. (2022) - Continuous theta burst stimulation for drug-resistant epilepsy
Craey E. et al. (2022) - Ex vivo feedback control of neurotransmission using a photocaged adenosine A1 receptor agonist
Mertens A. et al. (2022) - Investigating the effect of transcutaneous auricular vagus nerve stimulation on cortical excitability in healthy males
Bouckaert C. et al. (2022) - Laryngeal muscle-evoked potential recording as an indicator of vagal nerve fiber activation
Lescrauwaet E. et al. (2022) - Recent advances in the use of focused ultrasound as a treatment for epilepsy
Mertens A. et al. (2022) - The potential of invasive and non-invasive vagus nerve stimulation to improve verbal memory performance in epilepsy patients
Gadeyne S. et al (2022) - Transcutaneous auricular vagus nerve stimulation cannot modulate the P3b event-related potential in healthy volunteers
Christiaen E. et al (2022) - White matter integrity in a rat model of epileptogenesis : structural connectomics and fixel-based analysis
Poppa T. et al (2022) - Auricular transcutaneous vagus nerve stimulation modulates the heart-evoked potential
2021
Acharya A. et al. (2021) - Attenuation of hippocampal evoked potentials in vivo by activation of GtACR2, an optogenetic chloride channel
Schoeters R. et al. (2021) - Double two-state opsin model with autonomous parameter inference
Acharya A. et al. (2021) - In vivo blue light illumination for optogenetic inhibition : effect on local temperature and excitability of the rat hippocampus
Goossens M. et al. (2021) - Level of hM4D(Gi) DREADD expression determines inhibitory and neurotoxic effects in the hippocampus
Goossens M. et al. (2021) - Long‐term chemogenetic suppression of seizures in a multifocal rat model of temporal lobe epilepsy
Stevens L. et al. (2021) - Optimized parameters for transducing the locus coeruleus using canine adenovirus type 2 (CAV2) vector in rats for chemogenetic modulation research
Hödl S. et al. (2021) - Pre-ictal heart rate variability alterations in focal onset seizures and response to vagus nerve stimulation
Hödl S. et al. (2021) - Severe autonomic nervous system imbalance in Lennox-Gastaut syndrome patients demonstrated by heart rate variability recordings
Spanoghe J. et al. (2021) - The signaling pathways involved in the anticonvulsive effects of the adenosine A1 receptor
Dedeken P. et al. (2021) - High prevalence of epilepsy in Northern Rwanda : exploring gender differences
2020
Stevens L. et al. (2020) - A feasibility study to investigate chemogenetic modulation of the locus coeruleus by means of single unit activity
Germonpré C. et al (2020) - Acute symptomatic seizures following intracerebral hemorrhage in the rat collagenase model
Sprengers M. et al. (2020) - Deep brain stimulation reduces evoked potentials with a dual time course in freely moving rats : potential neurophysiological basis for intermittent as an alternative to continuous stimulation
Christiaen E. et al. (2020) - Dynamic functional connectivity and graph theory metrics in a rat model of temporal lobe epilepsy reveal a preference for brain states with a lower functional connectivity, segregation and integration
Van Lysebettens W. et al. (2020) - Identification of vagus nerve stimulation parameters affecting rat hippocampal electrophysiology without temperature effects
Hödl S. et al. (2020) - Neurophysiological investigations of drug resistant epilepsy patients treated with vagus nerve stimulation to differentiate responders from non-responders
Mertnes A. et al. (2020) - Transcutaneous vagus nerve stimulation does not affect verbal memory performance in healthy volunteers
2019
Christiaen E. et al. (2019) - Alterations in the functional brain network in a rat model of epileptogenesis : a longitudinal resting state fMRI study
Van Lysebettens W. et al. (2019) - Hypothermia masks most of the effects of rapid cycling VNS on rat hippocampal electrophysiology
De Sloovere J. et al. (2019) - Long-term chemogenetic suppression of spontaneous seizures in a mouse model for temporal lobe epilepsy.
2018
Mertens A. et al. (2018) - Recent advances in devices for vagus nerve stimulation
2017
Larsen L. et al. (2017) - Clinical vagus nerve stimulation paradigms induce pronounced brain and body hypothermia in rats
2016
Thyrion L. et al. (2016) - Disruption, but not overexpression of urate oxidase alters susceptibility to pentylenetetrazole- and pilocarpine-induced seizures in mice
Larsen L. et al. (2016) - Modulation of hippocampal activity by vagus nerve stimulation in freely moving rats
Carrette S. et al. (2016) - Repetitive transcranial magnetic stimulation for the treatment of refractory epilepsy
Buffel I. et al. (2016) - The effect of neuropeptide FF in the amygdala kindling model
Thyrion L. et al. (2016) - Uric acid is released in the brain during seizure activity and increases severity of seizures in a mouse model for acute limbic seizures
Larsen L. et al. (2016) - Vagus nerve stimulation applied with a rapid cycle has more profound influence on hippocampal electrophysiology than a standard cycle
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Brain cancer
Read more about our Brain cancer research here.
Saviuk M. et al. (2026) - Ferroptosis-armed dendritic cell vaccines for glioma immunotherapy
Bamelis A. et al. (2026) - Attract to kill : exploring the potential of motility trapping as a novel treatment strategy for high-grade gliomas
Curious how the technique works? This work is also featured in a news article with a video that explains it in an accessible way.
Van Hecke M. et al. (2025) - ELLIPSIS : robust quantification of splicing in scRNA-seq
Zoteva V. et al. (2024) - An improved F98 glioblastoma rat model to evaluate novel treatment strategies incorporating the standard of care
Lootens T. et al. (2024) - Glioblastoma-associated mesenchymal stem/stromal cells and cancer-associated fibroblasts : partners in crime?
Zoteva V. et al. (2024) - Integrating and optimizing tonabersat in standard glioblastoma therapy : a preclinical study
Bouckaert C. et al. (2021) - Comparison of in vivo and ex vivo magnetic resonance imaging in a rat model for glioblastoma-associated epilepsy
Bouckaert C. et al. (2020) - Development of a rat model for glioma-related epilepsy
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Cognition
Read more about our Cognition research here.
De Bie I. et al. (2025) - Noradrenergic agonists as treatment opportunity of radiation-induced cognitive decline
Theses
2026 - Targeting noradrenergic pathways to protect the juvenile brain against radiation-induced damage
2025 - Investigating the neuromodulatory potential of electrical and ultrasonic stimulation
2025 - Photopharmacological adenosine A1 receptor modulation for the suppression of epileptic seizures : a proof of concept
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Jeroen Spanoghe
2025 - Role of the locus coeruleus in modulation of hippocampal excitability in the healthy and epileptic brain
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Sielke Caestecker
2025 - Exploration of theta burst stimulation for the treatment of drug-resistant epilepsy
2024 - Computational modeling of optogenetic neuromodulation and neural recording for treatment of temporal lobe epilepsy
Ruben Schoeters
2024 - Exploring the therapeutic potential of vagus nerve stimulation in multiple sclerosis : insights from preclinical models
Helen Bachmann
2024 - Optical modulation of neuronal excitability using a novel photocaged adenosine A1 receptor agonist and its application in an ex vivo seizure model
Erine Craey
2022 - Investigating the perihematomal changes after intracerebral hemorrhage in the rat collagenase model using diffusion-weighted MRI and [18F]-FDG PET : a new approach for data-driven intensity normalization and voxel-based analysis of [18F]-FDG PET
Silke Proesmans
2022 - Optogenetic modulation of hippocampal excitability and seizures
Anirudh Acharya
2022 - Preclinical evaluation of chemogenetics as a new treatment for drug-resistant epilepsy
Jana Desloovere
2021 - Chemogenetic neuromodulation in a rat model of epilepsy
Marie-Gabrielle Goossens
2021 - Exploration of the effects of vagus nerve stimulation on tumor growth in a preclinical model for glioma-related epilepsy and identification of a marker for effective stimulation
Charlotte Bouckaert
2021 - Longitudinal structural and functional brain network changes during epileptogenesis in a rat model of temporal lobe epilepsy
Emma Christiaen
2021 - Optimization of chemogenetic modulation of the locus coeruleus in rat to study its relation to hippocampal excitability
Latoya Stevens
2021 - Post-stroke epilepsy in an animal model for intracerebral hemorrhage : optimization of the rat collagenase model
Charlotte Germonpré
2020 - Temperature as a confounder on vagus nerve stimulation induced brain excitability modulation in rats
Wouter Van Lysebettens
2016 - Investigation of a role for uric acid in experimental seizure models
Thyrion Lisa
2016 - Investigation of neurophysiological mechanisms of vagus nerve stimulation
Lars Emil Larsen
2016 - Use of functional neuroimaging and optogenetics to explore deep brain stimulation targets for the treatment of Parkinson's disease and epilepsy
Nathalie Van Den Berge