Imaging (PET/MRI)

Advanced pre-clinical imaging technologies play a key role in the neurological research conducted at the 4Brain lab. These imaging studies are carried out in the CORE ARTH Infinity facility, which provides specialized expertise and state-of-the-art imaging infrastructure. The imaging modalities that are frequently used include PET, CT, and MRI.

Positron Emission Tomography (PET) imaging is performed using the MOLECUBES β-CUBE. This technique can track radiolabelled compounds throughout the body and enables non-invasive visualization of biological processes. PET is particularly valuable for assessing novel diagnostic tracers, radiolabelled compounds, and targeted radionuclide therapies for brain tumours, such as glioblastoma. PET imaging is often complemented by X-ray Computed Tomography (CT) using the MOLECUBES X-CUBE, providing detailed three-dimensional anatomical information.

Magnetic Resonance Imaging (MRI) further enhances brain research by providing high-resolution images with excellent soft-tissue contrast. This technique allows detailed visualization of brain anatomy, tumours, and disease-related structural and functional changes, and is frequently used for accurate disease monitoring and longitudinal studies.

The integration of PET, CT, and MRI provides complementary functional and anatomical insights, enabling comprehensive characterization of neurological disease models and facilitating the development of innovative therapeutic strategies.